Background：Nucleocapsid (N) protein is the most abundant protein found in coronavirus.
CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways.
It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M.
E., et al.
2017, Virology; 517: 62-68).
The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics.
Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
仕様
サイズ：100ug
Source：HCoV-NL63 Nucleocapsid, His Tag (NUN-V5146) is expressed from E.coli cells. It contains AA Met 1 - His 377 (Accession # Q6Q1R8-1).
Molecule：Nucleocapsid protein
Synonyms：Nucleocapsid protein,NP,Protein N
Species：HCoV-NL63
Tag：His Tag
Expression Systems：E.coli
Expression Rigeion：Met 1 - His 377
Conjugate：Unconjugated
Molecular Weight：43.2 kDa
Characteristics：This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 43.2 kDa. The protein migrates as 50 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
