Background:Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus.
Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle.
Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding.
Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.
仕様
サイズ:100ug
Source:Influenza A [A/Thailand/1(KAN-1)/2004 (H5N1)] NA, His Tag (H54-V5247) is expressed from human 293 cells (HEK293). It contains AA His 36 - Lys 449 (Accession # H8PF47).
Molecule:Neuraminidase (NA)
Synonyms:NA,Neuraminidase
Species:Influenza
Tag:His Tag
Expression Systems:HEK293
Expression Rigeion:His 36 - Lys 449
Conjugate:Unconjugated
Molecular Weight:46.1 kDa
Characteristics:This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 46.1 kDa. The protein migrates as 50-57 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.