Background:Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus.
Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle.
Hemagglutinin also plays a major role in the determination of host range restriction and virulence.
As a class I viral fusion protein, hemagglutinin is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.
仕様
サイズ:100ug
Source:Influenza A [A/Hong Kong/483/97 (H5N1)] HA, His Tag (HA1-V5229) is expressed from human 293 cells (HEK293). It contains AA Asp 17 - Gln 531 (Accession # AAC32099.1).
Molecule:Hemagglutinin (HA)
Synonyms:HA,Hemagglutinin
Species:Influenza
Tag:His Tag
Expression Systems:HEK293
Expression Rigeion:Asp 17 - Gln 531
Conjugate:Unconjugated
Molecular Weight:60.1 kDa
Characteristics:This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 60.1 kDa. The protein migrates as 67-86 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.