Background:The OV16 antigen, localizes to the hypodermis, cuticle, and uterus of female O.
volvulus is regarded as a highly sensitive and specific antigen for detection of IgG4 in people with prior exposure to onchocerciasis.
It has an open reading frame that encodes a 152- amino acid polypeptide containing a 16-amino acid putative signal peptide.
Enzyme-linked Immunosorbent Assay serological testing of OV-16 antigen is a diagnostic tool for determining effective elimination of the parasite.
仕様
サイズ:100ug
Source:Onchocerca volvulus OV16, GST Tag (OV6-V51G4) is expressed from E.coli cells. It contains AA Lys 17 - Asp 197 (Accession # P31729-1).
Molecule:OV16
Synonyms:OV16,OV-16 antigen
Species:Onchocerca volvulus
Tag:GST Tag
Expression Systems:E.coli
Expression Rigeion:Lys 17 - Asp 197
Conjugate:Unconjugated
Molecular Weight:46.8 kDa
Characteristics:This protein carries a GST tag at the N-terminus. The protein has a calculated MW of 46.8 kDa. The protein migrates as 45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.