Background：It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor.
The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2.
S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor.
S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
仕様
サイズ：100ug
Source：SARS-CoV-2 Spike NTD (G75V, T76I, SYLTPGD 247-253 del), His Tag (SPD-C522b) is expressed from human 293 cells (HEK293). It contains AA Ser 13 - Leu 303 (G75V,T76I,SYLTPGD 247-253 del) (Accession # QHD43416.1). Mutations G75V, T76I, SYLTPGD 247-253 del were identified in the SARS-CoV-2 Lambda variant (Pango lineage: C.37).
Molecule：Spike NTD
Synonyms：S1 protein NTD,Spike protein S1 NTD,BetaCoV S1-NTD
Species：SARS-CoV-2
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Ser 13 - Leu 303 (G75V,T76I,SYLTPGD 247-253 del)
Conjugate：Unconjugated
Accession：QHD43416.1
Molecular Weight：34.2 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.2 kDa. The protein migrates as 45-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
