Background:Nucleocapsid (N) protein is the most abundant protein found in coronavirus.
CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways.
It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M.
E., et al.
2017, Virology; 517: 62-68).
The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics.
Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
仕様
サイズ:100ug
Source:SARS-CoV-2 Nucleocapsid Protein CTD, His Tag (NUN-C5145) is expressed from E.coli cells. It contains AA Ser 255 - Pro 364 (Accession # QHO62115.1).
Molecule:Nucleocapsid protein
Synonyms:Nucleocapsid protein,NP,Protein N
Species:SARS-CoV-2
Tag:His Tag
Expression Systems:E.coli
Expression Rigeion:Ser 255 - Pro 364
Conjugate:Unconjugated
Accession:QHO62115.1
Molecular Weight:13.4 kDa
Characteristics:This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 13.4 kDa. The protein migrates as 15 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.