Background:It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor.
The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2.
S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor.
S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
仕様
サイズ:100ug
Source:SARS-CoV-2 S protein RBD (Y453F), His Tag (SPD-C52Hk) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (Y453F)).
Molecule:Spike RBD
Synonyms:Spike,S protein RBD,Spike glycoprotein Receptor-binding domain,S glycoprotein RBD,Spike protein RBD
Species:SARS-CoV-2
Tag:His Tag
Expression Systems:HEK293
Expression Rigeion:Arg 319 - Lys 537
Conjugate:Unconjugated
Accession:QHD43416.1 (Y453F)
Molecular Weight:26.5 kDa
Characteristics:This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.5 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.