Background：During the formation of the coronaviral replication/transcription complex, essential steps include processing of the conserved polyprotein nsp7-10 region by the main protease Mpro and subsequent complex formation of the released nsp's.
Upon infecting host cells, coronaviruses assemble a multi-subunit RNA-synthesis complex of viral non-structural proteins (nsp) responsible for the replication and transcription of the viral genome.
non-structural proteins 7 (NSP7) forms a hexadecamer with nsp8 (8 subunits of each) that may participate in viral replication by acting as a primase.
Alternatively, may synthesize substantially longer products than oligonucleotide primers.
仕様
サイズ：100ug
Source：SARS-CoV-2 NSP7, His Tag (NS7-C51H6) is expressed from E.coli cells. It contains AA Ser 1 - Gln 83 (Accession # YP_009725303.1).
Molecule：NSP7
Synonyms：NSP7,nsp7,Non-structural protein 7
Species：SARS-CoV-2
Tag：His Tag
Expression Systems：E.coli
Expression Rigeion： Ser 1 - Gln 83
Conjugate：Unconjugated
Accession：YP_009725303.1
Molecular Weight：11.3 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 11.3 kDa. The protein migrates as 12 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
