Background:It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor.
The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2.
S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor.
S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
仕様
サイズ:100ug
Source:SARS-CoV-2 S1 protein, His Tag (S1N-C52H3) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1).
Molecule:Spike S1
Synonyms:Spike,S1 protein,Spike glycoprotein Subunit1,S glycoprotein Subunit1,Spike protein S1
Species:SARS-CoV-2
Tag:His Tag
Expression Systems:HEK293
Expression Rigeion:Val 16 - Arg 685
Conjugate:Unconjugated
Accession:QHD43416.1
Molecular Weight:76.9 kDa
Characteristics:This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 76.9 kDa. The protein migrates as 100-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.