86-7919-22 ［取扱停止］Human CCL2 / MCP-1 Protein, Fc Tag (MALS verified) 50ug CC2-H5255
特徴
- Background：Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes.
- The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide.
- CCL2, a member of the CC subfamily, is characterized by two adjacent cysteine residues.
- CCL2 displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils.
- It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis.
- It binds to chemokine receptors CCR2 and CCR4.
- Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
仕様
- サイズ：50ug
- Source：Human CCL2, Fc Tag (CC2-H5255) is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Thr 99 (Accession # P13500-1).
- Molecule：CCL2
- Synonyms：CCL2/C-C motif chemokine 2/MCP-1/MCAF
- Species：Human
- Tag：Fc Tag
- Expression Systems：HEK293
- Expression Rigeion：Gln 24 - Thr 99
- Conjugate：Unconjugated
- Accession：NP_002973.1
- Molecular Weight：35.1 kDa
- Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 35.1 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>90% as determined by SDS-PAGE.
- Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
- Package Size：50ug*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-7919-21
Human CCL2 / MCP-1 Protein, Fc Tag (MALS verified) 20ug
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86-7919-22
Human CCL2 / MCP-1 Protein, Fc Tag (MALS verified) 50ug
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