86-7919-07 ［取扱停止］Rat PTK7 / CCK4 Protein, His Tag (MALS verified) 100ug PT7-R52H6
特徴
Background：PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes.
Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle.
Also expressed in erythroleukemia cells.
Inactive tyrosine kinase involved in Wnt signaling pathway.
Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway.
Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis.
Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
仕様
サイズ：100ug
Source：Rat PTK7, His Tag (PT7-R52H6) is expressed from human 293 cells (HEK293). It contains AA Ala 23 - Gln 695 (Accession # NP_001382670.1).
Molecule：PTK7
Synonyms：PTK7,CCK4,CCK-4,Tyrosine-protein kinase-like 7,Protein-tyrosine kinase 7,Protein-tyrosine kinase 7
Species：Rat
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Ala 23 - Gln 695
Conjugate：Unconjugated
Accession：NP_001382670.1
Molecular Weight：76.1 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 76.1 kDa. The protein migrates as 95-116 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>95% as determined by SDS-PAGE.
Buffer：PBS, pH7.4
Package Size：100ug*1
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