86-7919-06 ［取扱停止］Rat PTK7 / CCK4 Protein, Fc Tag 100ug PT7-R5255
特徴
Background：PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes.
Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle.
Also expressed in erythroleukemia cells.
Inactive tyrosine kinase involved in Wnt signaling pathway.
Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway.
Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis.
Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
仕様
サイズ：100ug
Source：Rat PTK7, Fc Tag (PT7-R5255) is expressed from human 293 cells (HEK293). It contains AA Ala 23 - Gln 695 (Accession # NP_001382670.1).
Molecule：PTK7
Synonyms：PTK7,CCK4,CCK-4,Tyrosine-protein kinase-like 7,Protein-tyrosine kinase 7,Protein-tyrosine kinase 7
Species：Rat
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Ala 23 - Gln 695
Conjugate：Unconjugated
Accession：NP_001382670.1
Molecular Weight：100.7 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 100.7 kDa. The protein migrates as 120-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 0.1 EU per ug by the LAL method.
Purity：>95% as determined by SDS-PAGE.
Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Package Size：100ug*1
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