86-7918-73 ［取扱停止］Human uPAR / PLAUR Protein, Fc Tag (MALS verified) 1mg UPR-H5254
特徴
- Background：Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87.
- PLAUR contains three UPAR/Ly6 domains.
- U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain.
- PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1.
- PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation.
- U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.
仕様
- サイズ：1mg
- Source：Human uPAR, Fc Tag (UPR-H5254) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Arg 303 (Accession # Q03405-1).
- Molecule：uPAR
- Synonyms：uPAR,PLAUR,CD87,MO3
- Species：Human
- Tag：Fc Tag
- Expression Systems：HEK293
- Expression Rigeion：Leu 23 - Arg 303
- Conjugate：Unconjugated
- Accession：NP_002650.1
- Molecular Weight：57.8 kDa
- Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 57.8 kDa. The protein migrates as 65-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>95% as determined by SDS-PAGE.
- Buffer：PBS, pH7.4
- Package Size：1mg*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-7918-74
Human uPAR / PLAUR Protein, Fc Tag (MALS verified) 200ug
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86-7918-73
Human uPAR / PLAUR Protein, Fc Tag (MALS verified) 1mg
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