86-7918-66 ［取扱停止］Human CLEC4C / BDCA2 Protein, Fc Tag 100ug CLC-H5254
特徴
Background：CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303.
Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell.
Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man.
Binds to serum IgG.
Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells.
May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells.
May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
仕様
サイズ：100ug
Source：Human CLEC4C, Fc Tag (CLC-H5254) is expressed from human 293 cells (HEK293). It contains AA Asn 45 - Ile 213 (Accession # Q8WTT0-1).
Molecule：CLEC4C
Synonyms：DLEC,CLEC4C,BDCA-2,CD303,CLECSF11,CLECSF7, HECL
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Asn 45 - Ile 213
Conjugate：Unconjugated
Accession：NP_569708.1
Molecular Weight：46.4 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 46.4 kDa. The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>95% as determined by SDS-PAGE.
Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Package Size：100ug*1
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