Background：Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family.
Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin.
Both MPF and the cleaved form of mesothelin are N-glycosylated.
Mesothelin / MSLN can interacts with MUC16.
The membrane-anchored forms of MSLN may play a role in cellular adhesion.
MPF potentiates megakaryocyte colony formation in vitro.
仕様
サイズ：25tests
Source：PE-Labeled Human Mesothelin (296-580), His Tag (MSN-HP2H5) is produced via site-specific conjugation of PE to Human Mesothelin (296-580), His Tag under optimal conditions with a proprietary technology. Human Mesothelin (296-580), His Tag is expressed in HEK293 cells containing AA Glu 296 - Gly 580 (Accession # AAH09272).
Molecule：Mesothelin
Synonyms：MSLN,Mesothelin,MPF
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Glu 296 - Gly 580
Conjugate：PE Labeled Protein
Accession： AAH09272.1
Molecular Weight：35.9 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 35.9 kDa.
