Background:Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily.
TNFRSF17 contains one TNFR-Cys repeat.
TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes.
TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL.
TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity.
TNFRSF17 can activate NF-kappa-B and JNK.
仕様
サイズ:100ug
Source:Rabbit BCMA, His Tag (BCA-R52H4) is expressed from human 293 cells (HEK293). It contains AA Gln 1 - Asn 52 (Accession # G1SFN4-1).
Molecule:BCMA
Synonyms:TNFRSF17,CD269,BCM,BCMA
Species:Rabbit
Tag:His Tag
Expression Systems:HEK293
Expression Rigeion:Gln 1 - Asn 52
Conjugate:Unconjugated
Molecular Weight:7.9 kDa
Characteristics:This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 7.9 kDa. The protein migrates as 12 kDa and 14 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.