Background：Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily.
TNFRSF17 contains one TNFR-Cys repeat.
TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes.
TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL.
TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity.
TNFRSF17 can activate NF-kappa-B and JNK.
仕様
サイズ：100ug
Source：Rat BCMA, His Tag (BCA-R52H3) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Thr 49 (Accession # D3ZKQ8-1).
Molecule：BCMA
Synonyms：TNFRSF17,CD269,BCM,BCMA
Species：Rat
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Met 1 - Thr 49
Conjugate：Unconjugated
Accession：NP_076975.2
Molecular Weight：7.6 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 7.6 kDa. The protein migrates as 10-15 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
