Background：CLEC2D (C-type lectin domain family 2 member D) is also known as CLAX, LLT1, OCIL is receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis, inhibits osteoclast formation, inhibits bone resorption and modulates the release of interferon-gamma.
It is also a ligand for the human NKR-P1A (CD161) receptor, present on NK cells and T cells.
Furthermore, The reference shows the pathway may as a potential immunotherapy targets.
仕様
サイズ：100ug
Source：Human CLEC2D, Mouse IgG2a Fc Tag (CLD-H5253) is expressed from human 293 cells (HEK293). It contains AA Arg 60 - Val 191 (Accession # Q9UHP7-1).
Molecule：CLEC2D
Synonyms：CLEC2D, C-type lectin domain family 2 member D, Lectin-like NK cell receptor, Lectin-like transcript 1, LLT-1, Osteoclast inhibitory lectin
Species：Human
Tag：Mouse IgG Fc Tag
Expression Systems：HEK293
Expression Rigeion： Arg 60 - Val 191
Conjugate：Unconjugated
Accession：NP_037401.1
Molecular Weight：42.2 kDa
Characteristics：This protein carries a mouse IgG2a Fc tag at the N-terminus. The protein has a calculated MW of 42.2 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 0.1 EU per ug by the LAL method.
Purity：>95% as determined by SDS-PAGE.
Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
