Background：Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains.
The LAG3 gene contains 8 exons.
The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.
LAG3 /CD223 involved in lymphocyte activation.
LAG3 /CD223 binds to HLA class-II antigens.
仕様
サイズ：25ug
Source：Biotinylated Mouse LAG-3, His,Avitag (LA3-M82E5) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Leu 442 (Accession # Q61790-1).
Molecule：LAG-3
Synonyms：LAG3,CD223,FDC
Species：Mouse
Tag：His Tag & Avi Tag
Expression Systems：HEK293
Expression Rigeion：Gly 24 - Leu 442
Conjugate：Precision Avi
Accession：NP_032505.1
Molecular Weight：48.8 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag). The protein has a calculated MW of 48.8 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
