Background:The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands.
The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4).
Mutations affecting EGFR expression or activity could result in cancer.
仕様
サイズ:25tests
Source:PE-Labeled Human EGF R, His Tag (EGR-HP2E3) is produced via site-specific conjugation of PE to Human EGF R, His Tag under optimal conditions with a proprietary technology. Human EGF R, His Tag is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Ser 645 (Accession # P00533-1).
Molecule:EGF R
Synonyms:EGFR,ERBB,ERBB1,HER1,PIG61,mENA
Species:Human
Tag:His Tag
Expression Systems:HEK293
Expression Rigeion:Leu 25 - Ser 645
Conjugate:PE Labeled Protein
Accession:NP_005219.2
Molecular Weight:72.3 kDa
Characteristics:This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 72.3 kDa.