Background：Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily.
Cadherins are calcium-dependent cell adhesion proteins.
They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
CDH6 / KCAD contains five cadherin domains.
CDH6 is highly expressed in brain, cerebellum, and kidney.
Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.
仕様
サイズ：100ug
Source：Human Cadherin-6 Protein, Fc Tag (CA6-H5258) is expressed from human 293 cells (HEK293). It contains AA Thr 19 - Ala 615 (Accession # P55285-1).
Molecule：Cadherin-6
Synonyms：CDH6,CAD6,KCAD,K-cadherin,Cadherin-6
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Thr 19 - Ala 615
Conjugate：Unconjugated
Accession：NP_004923.1
Molecular Weight：92.8 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 92.8 kDa. The protein migrates as 100-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>90% as determined by SDS-PAGE.
Buffer：50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
