Background：Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87.
PLAUR contains three UPAR/Ly6 domains.
U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain.
PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1.
PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation.
U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.
仕様
サイズ：25ug
Source：FITC-Labeled Human uPAR, His Tag (UPR-HF2H3) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Arg 303 (Accession # Q03405-1).
Molecule：uPAR
Synonyms：uPAR,PLAUR,CD87,MO3
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Leu 23 - Arg 303
Conjugate：FITC Labeled Protein
Accession：NP_002650.1
Molecular Weight：32.3 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 32.3 kDa. The protein migrates as 45-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
