Background：CD24 may have a pivotal role in cell differentiation of different cell types.
Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor.
Modulates B-cell activation responses.
Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90.
Plays a role in the control of autoimmunity.
仕様
サイズ：100ug
Source：Human CD24, His tag (Nanoparticle) (CD4-H52H5) is expressed from human 293 cells (HEK293). It contains AA Ser 27 - Gly 59 (Accession # P25063-1).
Molecule：CD24
Synonyms：CD24,CD24A
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Ser 27 - Gly 59
Conjugate：Unconjugated
Accession：NP_001278666.1
Molecular Weight：34.3 kDa
Characteristics：Human CD24 Protein, His tag (Nanoparticle) is designed and expressed as nanoparticles of approximately 25 nm diameter by displaying CD24 ECD in native conformation. The nanoparticles each was coated with an average of 180 CD24 ECD.
The nanoparticle technology allows directional and high-density display of human CD24 on the surface of nanoparticles, thus greatly enhances the immune response in vivo to otherwise poorly immunogenic epitopes.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.3 kDa. The protein migrates as 43-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 0.5 EU per ug by the LAL method.
