Background：Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases.
It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron(III).
Taking into account its high specificity and overexpression in human cancers, STEAP1 is nowadays a promising candidate to be imposed as a therapeutic target.
仕様
サイズ：20ug
Source：Human STEAP1 Full Length, His Tag (HEK293) (ST1-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 2 - Leu 339 (Accession # Q9UHE8-1).
Molecule：STEAP1
Synonyms：STEAP1, PRSS24, STEAP
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Gln 2 - Leu 339
Conjugate：Unconjugated
Accession：NP_036581.1
Molecular Weight：41.7 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 41.7 kDa. The protein migrates as 31 kDa and 35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
