86-7917-57 [取扱停止]Human PTK7 / CCK4 Protein, Fc Tag (MALS verified) 100ug PT7-H5253
特徴
Background:PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes.
Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle.
Also expressed in erythroleukemia cells.
Inactive tyrosine kinase involved in Wnt signaling pathway.
Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway.
Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis.
Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
仕様
サイズ:100ug
Source:Human PTK7, Fc Tag (PT7-H5253) is expressed from human 293 cells (HEK293). It contains AA Ala 31 - Thr 704 (Accession # Q13308-1).
Molecule:PTK7
Synonyms:PTK7,CCK4,CCK-4,Tyrosine-protein kinase-like 7,Protein-tyrosine kinase 7,Protein-tyrosine kinase 7
Species:Human
Tag:Fc Tag
Expression Systems:HEK293
Expression Rigeion:Ala 31 - Thr 704
Conjugate:Unconjugated
Accession:NP_002812.2
Molecular Weight:101.1 kDa
Characteristics:This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 101.1 kDa. The protein migrates as 125-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.
Purity:>95% as determined by SDS-PAGE.
Buffer:50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Package Size:100ug*1
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