86-7917-21 ［取扱停止］Mouse CLEC12A / MICL / CLL-1 Protein, His Tag 100ug CLA-M5244
特徴
Background：CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL.
Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death.
Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years.
The role of CLEC12A in MDS, however, remains to be elucidated.
Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.
仕様
サイズ：100ug
Source：Mouse CLEC12A, His Tag (CLA-M5244) is expressed from human 293 cells (HEK293). It contains AA Tyr 65 - Arg 267 (Accession # Q504P2-1).
Molecule：CLEC12A
Synonyms：CLEC12A,MICL,CLL-1,CLL1,DCAL2,DCAL-2,CD371
Species：Mouse
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Tyr 65 - Arg 267
Conjugate：Unconjugated
Molecular Weight：25.7 kDa
Characteristics：This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 25.7 kDa. The protein migrates as 30-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>90% as determined by SDS-PAGE.
Buffer：PBS, pH7.4
Package Size：100ug*1
この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
【試薬に関するお問合せ】
アズワン株式会社 試薬・プロセス材料グループ
TEL：06-6447-8641
FAX：06-6447-8642
E-mail：[email protected]
