Background：Human B7 homolog 3 (B7-H3) is a member of the B7 family of immune proteins that provide signals for the regulation of immune responses.
Other family members include B7-1, B7-2, B7-H1/PD-L1, B7-H2, and PD-L2.
B7 family proteins are type I transmembrane immunoglobulin (Ig) superfamily members that contain extracellular Ig V‑like and Ig C‑like domains with a short cytoplasmic tail.
Termed 4IgB7-H3 or B7-H3b, this molecule has two additional Ig-like domains (one V‑type and one C‑type) and shows a ubiquituous expression pattern.
仕様
サイズ：25ug
Source：FITC-Labeled Human B7-H3 (4Ig), His Tag (B7B-HF2E7) is expressed from human 293 cells (HEK293). It contains AA Gly 27 - Thr 461 (Accession # Q5ZPR3-1). It is the FITC labeled form of Human B7-H3 (4Ig), His Tag (Cat. No.B7B-H52E7).
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 48.5 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
