Background:Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family.
NCR1 contains two Ig-like (immunoglobulin-like) domains.
NCR1 interacts with CD247 and FCER1G.
NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
仕様
サイズ:100ug
Source:Cynomolgus NKp46, Llama IgG2b Fc Tag (NC1-C5255) is expressed from human 293 cells (HEK293). It contains AA Pro 22 - Arg 257 (Accession # Q95JB9-1).
Molecule:NKp46
Synonyms:NCR1,LY94,CD335,NK-p46,hNKp46
Species:Cynomolgus
Tag:Llama IgG Fc Tag
Expression Systems:HEK293
Expression Rigeion:Pro 22 - Arg 257
Conjugate:Unconjugated
Accession:NP_001271509.1
Molecular Weight:54.7 kDa
Characteristics:This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 54.7 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 0.01 EU per ug by the LAL method.
Purity:>90% as determined by SDS-PAGE.
Buffer:50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5