Background:Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily.
TNFRSF17 contains one TNFR-Cys repeat.
TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes.
TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL.
TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity.
TNFRSF17 can activate NF-kappa-B and JNK.
仕様
サイズ:25tests
Source:PE-Labeled Human BCMA, His Tag (BCA-HP2H2) is produced via site-specific conjugation of PE to Human BCMA, His Tag under optimal conditions with a proprietary technology. Human BCMA, His Tag is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 54 (Accession # Q02223-1).
Molecule:BCMA
Synonyms:TNFRSF17,CD269,BCM,BCMA
Species:Human
Tag:His Tag
Expression Systems:HEK293
Expression Rigeion:Met 1 - Ala 54
Conjugate:PE Labeled Protein
Accession:NP_001183.2
Molecular Weight:10 kDa
Characteristics:This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 10 kDa.