Background：Syndecan-1 (SYND1 or SDC1) is also known as CD antigen CD138, is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family.
The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein.
The syndecan-1 / SDC1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins.
It is a useful marker for plasma cells, but only if the cells tested are already known to be derived from blood.
仕様
サイズ：100ug
Source：Human Syndecan-1, Fc Tag (SY1-H5253) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Gly 254 (Accession # P18827-1).
Molecule：Syndecan-1
Synonyms：SDC1,Syndecan-1,CD138,SYND1,SDC
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion： Gln 23 - Gly 254
Conjugate：Unconjugated
Molecular Weight：50.3 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.3 kDa. The protein migrates as 65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
