Background：Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker.
TNFRSF-8 is expressed by activated, but not by resting, T and B cells.
Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15.
CD30 is the receptor for TNFSF8/CD30L.
CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B.
TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts.
TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.
仕様
サイズ：25ug
Source：FITC-Labeled Human CD30, His Tag (Cat. No. CD0-HF250) is expressed from human HEK293 cells. It contains AA Phe 19 - Lys 379 (Accession # NP_001234.2). It is the FITC labeled form of Human CD30, His Tag (Cat. No.CD0-H5250).
Molecule：CD30
Synonyms：TNFRSF8,CD30,D1S166E,Ki-1
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Phe 19 - Lys 379
Conjugate：FITC Labeled Protein
Accession：NP_001234.2
Molecular Weight：64.6 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 64.6 kDa. The protein migrates as 70-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
