Background：T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3.
CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain.
CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction.
CD4 induces the aggregation of lipid rafts.
CD4 is a primary receptor used by HIV-1 to gain entry into host T cells.
HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors.
Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.
仕様
サイズ：25tests
Source：PE-Labeled Human CD4, His Tag (CD4-HP2E3) is produced via site-specific conjugation of PE to Human CD4, His Tag under optimal conditions with a proprietary technology. Human CD4, His Tag is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Pro 396 (Accession # P01730-1).
Molecule：CD4
Synonyms：CD4,CD4mut,LEU3
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Lys 26 - Pro 396
Conjugate：PE Labeled Protein
Accession：NP_000607.1
Molecular Weight：45.0 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 45.0 kDa.
