Background：CD209 is also known as CLEC4L, DC-SIGN and CD209 antigen.
Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response.
On DCs it is a high affinity receptor for ICAM2 and ICAM3 by binding to mannose-like carbohydrates.
May act as a DC rolling receptor that mediates transendothelial migration of DC presursors from blood to tissues by binding endothelial ICAM2.
Seems to regulate DC-induced T-cell proliferation by binding to ICAM3 on T-cells in the immunological synapse formed between DC and T-cells.
仕様
サイズ：100ug
Source：Human CD209, His Tag (CD9-H5246) is expressed from human 293 cells (HEK293). It contains AA Gln 59 - Ala 404 (Accession # Q9NNX6-1).
Molecule：CD209
Synonyms：DC-SIGN,CD209,DC-SIGN1,CLEC4L
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Gln 59 - Ala 404
Conjugate：Unconjugated
Accession：NP_066978.1
Molecular Weight：41.3 kDa
Characteristics：This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 41.3 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
