Background：CD24 may have a pivotal role in cell differentiation of different cell types.
Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor.
Modulates B-cell activation responses.
Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90.
Plays a role in the control of autoimmunity.
仕様
サイズ：100ug
Source：Human CD24, Mouse IgG2a Fc Tag (CD4-H5257) is expressed from human 293 cells (HEK293). It contains AA Ser 27 - Gly 59 (Accession # P25063-1).
Molecule：CD24
Synonyms：CD24,CD24A
Species：Human
Tag：Mouse IgG Fc Tag
Expression Systems：HEK293
Expression Rigeion：Ser 27 - Gly 59
Conjugate：Unconjugated
Accession：NP_001278666.1
Molecular Weight：30.0 kDa
Characteristics：This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 30.0 kDa. The protein migrates as 40-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 0.1 EU per ug by the LAL method.
Purity：>90% as determined by SDS-PAGE.
Buffer：50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
