Background:CD24 may have a pivotal role in cell differentiation of different cell types.
Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor.
Modulates B-cell activation responses.
Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90.
Plays a role in the control of autoimmunity.
仕様
サイズ:100ug
Source:Human CD24, His Tag (CD4-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 27 - Gly 59 (Accession # P25063-1).
Molecule:CD24
Synonyms:CD24,CD24A
Species:Human
Tag:His Tag
Expression Systems:HEK293
Expression Rigeion:Ser 27 - Gly 59
Conjugate:Unconjugated
Accession:NP_001278666.1
Molecular Weight:5.0 kDa
Characteristics:This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 5.0 kDa. The protein migrates as 19-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.