Background:CD160 antigen is also known as natural killer cell receptor BY55, is a 27 kDa glycoprotein, contains 1 Ig-like V-type (immunoglobulin-like) domain.
Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity.
CD160 is expressed at the cell surface as a tightly disulfide-linked multimer.
In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes.
CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.
When expressed on vascular endothelial cells, CD160 propagates anti-angiogenic signals and promotes apoptosis.
仕様
サイズ:100ug
Source:Human CD160, His Tag (BY5-H5229) is expressed from human 293 cells (HEK293). It contains AA Ile 27 - Ser 159 (Accession # O95971-1).
Molecule:CD160
Synonyms:CD160,BY55,NK1,NK28
Species:Human
Tag:His Tag
Expression Systems:HEK293
Expression Rigeion:Ile 27 - Ser 159
Conjugate:Unconjugated
Accession:NP_008984.1
Molecular Weight:16.7 kDa
Characteristics:This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 16.7 kDa. The protein migrates as 25-28 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.