Background：Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily.
TNFRSF17 contains one TNFR-Cys repeat.
TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes.
TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL.
TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity.
TNFRSF17 can activate NF-kappa-B and JNK.
仕様
サイズ：100ug
Source：Human BCMA, Mouse IgG2a Fc Tag (BCA-H5253) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 54 (Accession # Q02223-1).
Molecule：BCMA
Synonyms：TNFRSF17,CD269,BCM,BCMA
Species：Human
Tag：Mouse IgG Fc Tag
Expression Systems：HEK293
Expression Rigeion：Met 1 - Ala 54
Conjugate：Unconjugated
Accession：NP_001183.2
Molecular Weight：32.8 kDa
Characteristics：This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 32.8 kDa. The protein migrates as 35-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 0.1 EU per ug by the LAL method.
Purity：>90% as determined by SDS-PAGE.
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
