Background：DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains.
DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells.
DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation.
Furthermore, DNAM-1 can interact with PVR and PVRL2.
仕様
サイズ：100ug
Source：Cynomolgus DNAM-1, His Tag (DN1-C52H9) is expressed from human 293 cells (HEK293). It contains AA Glu 19 - Phe 252 (Accession # A0A2K5W1Z6-1).
Molecule：DNAM-1
Synonyms：DNAM1,CD226,PTA1
Species：Cynomolgus
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Glu 19 - Phe 252
Conjugate：Unconjugated
Accession：XP_005586537.1
Molecular Weight：28.5 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.5 kDa. The protein migrates as 40-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
