Background:Butyrophilin subfamily 3 member A2(BTN3A2/BT3.2) mRNA expression by tumoral cells was previously identified as a prognostic factor in a small cohort of high grade serous epithelial ovarian cancer (HG-EOC).
We find that the three BTN3A isoforms: BTN3A1, BTN3A2, and BTN3A3, have high structural homology to the B7 superfamily of proteins and exist as V-shaped homodimers in solution, associating through the membrane proximal C-type Ig domain.
仕様
サイズ:25ug
Source:Biotinylated Human BTN3A2, His,Avitag (BT2-H82E7) is expressed from human 293 cells (HEK293). It contains AA Gln 30 - Trp 248 (Accession # P78410-1).
Molecule:BTN3A2
Synonyms:BT3.2,BT3.3,BTF3,BTF4
Species:Human
Tag:His Tag & Avi Tag
Expression Systems:HEK293
Expression Rigeion:Gln 30 - Trp 248
Conjugate:Precision Avi
Accession: NP_001184175.1
Molecular Weight:27.3 kDa
Characteristics:This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag). The protein has a calculated MW of 27.3 kDa. The protein migrates as 30-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.