Background：Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains.
The LAG3 gene contains 8 exons.
The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.
LAG3 /CD223 involved in lymphocyte activation.
LAG3 /CD223 binds to HLA class-II antigens.
仕様
サイズ：100ug
Source：Cynomolgus LAG-3, Mouse IgG2a Fc tag (LA3-C52A0) is expressed from human 293 cells (HEK293). It contains AA Ala 18 - His 449 (Accession # XP_005570011.1).
Molecule：LAG-3
Synonyms：LAG3,CD223,FDC
Species：Cynomolgus
Tag：Mouse IgG Fc Tag
Expression Systems：HEK293
Expression Rigeion：Ala 18 - His 449
Conjugate：Unconjugated
Accession：XP_005570011.1
Molecular Weight：73.5 kDa
Characteristics：This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 73.5 kDa. The protein migrates as 95 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>90% as determined by SDS-PAGE.
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
