Background:Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily.
TNFRSF17 contains one TNFR-Cys repeat.
TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes.
TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL.
TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity.
TNFRSF17 can activate NF-kappa-B and JNK.
仕様
サイズ:100ug
Source:Cynomolgus / Rhesus macaque BCMA, His Tag (BCA-C52H7) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 53 (Accession # G7Q0I4-1). In the region Met 1 - Ala 53, the AA sequence of Cynomolgus and Rhesus macaque BCMA are homologus.
Molecule:BCMA
Synonyms:TNFRSF17,CD269,BCM,BCMA
Species:Cynomolgus / Rhesus macaque
Tag:His Tag
Expression Systems:HEK293
Expression Rigeion:Met 1 - Ala 53
Conjugate:Unconjugated
Accession:XP_005591343.1
Molecular Weight:7.9 kDa
Characteristics:This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 7.9 kDa. The protein migrates as 14-16 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.