Background:Butyrophilin subfamily 3 member A1 (BTN3A1) is also known as CD277 and BTF5, which belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains.
BTN3A1 plays a role in T-cell activation and in the adaptive immune response.
Also, BTN3A1 regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells.
Furthermore, BTN3A1 mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.
仕様
サイズ:25ug
Source:Biotinylated Human BTN3A1, Fc,Avitag (BT1-H82F7) is expressed from human 293 cells (HEK293). It contains AA Gln 30 - Gly 254 (Accession # O00481-1).
Molecule:BTN3A1
Synonyms:BTN3A1,CD277,BTF5
Species:Human
Tag:Fc Tag & Avi Tag
Expression Systems:HEK293
Expression Rigeion:Gln 30 - Gly 254
Conjugate:Precision Avi
Accession:NP_008979.3
Molecular Weight:52.93 kDa
Characteristics:This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag). The protein has a calculated MW of 52.93 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.
Purity:>95% as determined by SDS-PAGE.
Buffer:Tris with Glycine, Arginine and NaCl, pH7.5