Background：Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family.
Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin.
Both MPF and the cleaved form of mesothelin are N-glycosylated.
Mesothelin / MSLN can interacts with MUC16.
The membrane-anchored forms of MSLN may play a role in cellular adhesion.
MPF potentiates megakaryocyte colony formation in vitro.
仕様
サイズ：100ug
Source：Human Mesothelin (296-580), Fc Tag (MSN-H5253) is expressed from human 293 cells (HEK293). It contains AA Glu 296 - Gly 580 (Accession # AAH09272.1).
Molecule：Mesothelin
Synonyms：MSLN,Mesothelin,MPF
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Glu 296 - Gly 580
Conjugate：Unconjugated
Accession：AAH09272.1
Molecular Weight：58.6 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 58.6 kDa. The protein migrates as 66-85 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 0.1 EU per ug by the LAL method.
