Background：Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily.
TNFRSF17 contains one TNFR-Cys repeat.
TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes.
TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL.
TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity.
TNFRSF17 can activate NF-kappa-B and JNK.
仕様
サイズ：25ug
Source：Biotinylated Mouse BCMA, Fc,Avitag (BCA-M82F0) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Thr 49 (Accession # O88472-1).
Molecule：BCMA
Synonyms：TNFRSF17,CD269,BCM,BCMA
Species：Mouse
Tag：Fc Tag & Avi Tag
Expression Systems：HEK293
Expression Rigeion：Met 1 - Thr 49
Conjugate：Precision Avi
Accession：NP_035738.1
Molecular Weight：34.4 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag). The protein has a calculated MW of 34.4 kDa. The protein migrates as 38-50 kDa under reducing (R) condition (SDS-PAGE) due to O-linked glycosylation which has been verified by O-Glycosidase and Neuraminidase digestion.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>90% as determined by SDS-PAGE.
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
