86-7912-67 ［取扱停止］Biotinylated Human Mesothelin / MSLN (296-580) Protein, His,Avitag (MALS verified) 25ug MSN-H82E9
特徴
- Background：Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family.
- Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin.
- Both MPF and the cleaved form of mesothelin are N-glycosylated.
- Mesothelin / MSLN can interacts with MUC16.
- The membrane-anchored forms of MSLN may play a role in cellular adhesion.
- MPF potentiates megakaryocyte colony formation in vitro.
仕様
- サイズ：25ug
- Source：Biotinylated Human Mesothelin (296-580), His,Avitag (MSN-H82E9) is expressed from human 293 cells (HEK293). It contains AA Glu 296 - Gly 580 (Accession # AAH09272.1).
- Molecule：Mesothelin
- Synonyms：MSLN,Mesothelin,MPF
- Species：Human
- Tag：His Tag & Avi Tag
- Expression Systems：HEK293
- Expression Rigeion：Glu 296 - Gly 580
- Conjugate：Precision Avi
- Accession：AAH09272.1
- Molecular Weight：35.9 kDa
- Characteristics：This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag). The protein has a calculated MW of 35.9 kDa. The protein migrates as 38-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>95% as determined by SDS-PAGE.
- Buffer：PBS, pH7.4
- Package Size：25ug*1
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