Background:Leukocyte immunoglobulin-like receptor subfamily B member 3 is also known as LILRB3,ILT-5 or CD85a.
LILRB3 plays an role as receptor for class I MHC antigens, which activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor.
LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands.
LILRB3 can mediate inhibitory signaling via immunoreceptor tyrosine-based inhibition motifs in its cytoplasmic tail whereas LILRA6 can signal through association with an activating adaptor molecule, FcRγ.
仕様
サイズ:100ug
Source:Human LILRB3, His Tag (CDA-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Glu 443 (Accession # AAB68668 (P288R)).
Molecule:LILRB3
Synonyms:LILRB3,CD85a,ILT5
Species:Human
Tag:His Tag
Expression Systems:HEK293
Expression Rigeion:Gly 24 - Glu 443
Conjugate:Unconjugated
Accession:AAB68668 (P288R)
Molecular Weight:48 kDa
Characteristics:This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 48 kDa. The protein migrates as 60-78 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.