Background:Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5), also known as CD85c and LIR-8, belongs to the leukocyte immunoglobulin-like receptor (LIR) family of transmembrane glycoproteins that negatively regulate immune cell activation.
Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response.
仕様
サイズ:25ug
Source:Biotinylated Human LILRB5, Fc,Avitag (CDC-H82F8) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Gly 458 (Accession # O75023-1).
Molecule:LILRB5
Synonyms:LILRB5,CD85c,LIR-8
Species:Human
Tag:Fc Tag & Avi Tag
Expression Systems:HEK293
Expression Rigeion:Gly 24 - Gly 458
Conjugate:Precision Avi
Accession:NP_006831.1
Molecular Weight:75.8 kDa
Characteristics:This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag). The protein has a calculated MW of 75.8 kDa. The protein migrates as 90-105 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.
Purity:>95% as determined by SDS-PAGE.
Buffer:Tris with Glycine, Arginine and NaCl, pH7.5