Background：Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) is also known as CD85 antigen-like family member D (CD85d), Immunoglobulin-like transcript 4 (ILT-4), Monocyte / macrophage immunoglobulin-like receptor 10 (MIR-10), which is a member of the the subfamily B class of LIR receptors.
LILRB2 is receptor for class I MHC antigens.
LILRB2 recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.
LILRB2 competes with CD8A for binding to class I MHC antigens.
LILRB2 / CD85d inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
仕様
サイズ：100ug
Source：Human LILRB2, Fc Tag (CDD-H5259) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Val 461 (Accession # AAH36827).
Molecule：LILRB2
Synonyms：LILRB2,ILT4,LIR2,MIR10,CD85d
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Gln 22 - Val 461
Conjugate：Unconjugated
Accession：AAH36827
Molecular Weight：74.4 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 74.4 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>90% as determined by SDS-PAGE.
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
