Background：Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily.
TNFRSF17 contains one TNFR-Cys repeat.
TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes.
TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL.
TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity.
TNFRSF17 can activate NF-kappa-B and JNK.
仕様
サイズ：25ug
Source：Biotinylated Cynomolgus / Rhesus macaque BCMA, Fc,Avitag (BCA-C82F4) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 53 (Accession # G7Q0I4-1). In the region Met 1 - Ala 53, the AA sequence of Cynomolgus and Rhesus macaque BCMA are homologus.
Molecule：BCMA
Synonyms：TNFRSF17,CD269,BCM,BCMA
Species：Cynomolgus / Rhesus macaque
Tag：Fc Tag & Avi Tag
Expression Systems：HEK293
Expression Rigeion：Met 1 - Ala 53
Conjugate：Precision Avi
Accession：XP_005591343.1
Molecular Weight：33.9 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag). The protein has a calculated MW of 33.9 kDa. The protein migrates as 42-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>95% as determined by SDS-PAGE.
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
