86-7912-18 ［取扱停止］Biotinylated Human CD38 Protein, Avitag,His Tag 25ug CD8-H82E7
特徴
- Background：CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family.
- CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
- CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose.
- These reaction products are essential for the regulation of intracellular Ca2+.
- The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications.
- The CD38 protein is a marker of cell activation.
- It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism.
- CD38 has been used as a prognostic marker in leukemia.
仕様
- サイズ：25ug
- Source：Biotinylated Human CD38, Avitag,His Tag (CD8-H82E7) is expressed from human 293 cells (HEK293). It contains AA Val 43 - Ile 300 (Accession # NP_001766.2).
- Molecule：CD38
- Synonyms：CD38,T10,cADPr hydrolase 1
- Species：Human
- Tag：His Tag & Avi Tag
- Expression Systems：HEK293
- Expression Rigeion：Val 43 - Ile 300
- Conjugate：Precision Avi
- Accession：NP_001766.2
- Molecular Weight：32.5 kDa
- Characteristics：This protein carries an Avi tag (Avitag) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 32.5 kDa. The protein migrates as 40-48 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>90% as determined by SDS-PAGE.
- Buffer：PBS, pH7.4
- Package Size：25ug*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7912-18
Biotinylated Human CD38 Protein, Avitag,His Tag 25ug
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86-7912-19
Biotinylated Human CD38 Protein, Avitag,His Tag 200ug
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